Recent advances in the study of tomato Cf resistance genes

Rivas, Susana and Thomas, Colwyn M. (2002) Recent advances in the study of tomato Cf resistance genes. Molecular Plant Pathology, 3 (4). pp. 277-282. ISSN 1364-3703

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Tomato Cf genes confer resistance to the leaf mould pathogen Cladosporium fulvum through recognition of distinct fungal-encoded avirulence (Avr) peptides secreted into the leaf apoplast during infection. These Avr determinants are small cysteine-rich proteins that exhibit no primary sequence homology (Luderer and Joosten, 2001). The tomato–C. fulvum interaction is an attractive model system to study the molecular basis of recognition specificity in plant disease resistance (R) proteins, and R-protein mediated defence responses. Cf proteins are type I transmembrane glycoproteins comprised predominantly of extracytoplasmic leucine-rich repeats (LRRs), a membrane-spanning region, and a short cytoplasmic domain that lacks an obvious signalling function (reviewed in Thomas et al., 1998). These R proteins activate a hypersensitive response (HR) upon recognition of their cognate Avr proteins.

Item Type: Article
Faculty \ School: Faculty of Science > School of Biological Sciences
UEA Research Groups: Faculty of Science > Research Groups > Plant Sciences
Depositing User: EPrints Services
Date Deposited: 01 Oct 2010 13:37
Last Modified: 15 Dec 2022 01:42
DOI: 10.1046/j.1364-3703.2002.00116.x

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