Small RNA analysis in Sindbis virus infected human HEK293 cells

Donaszi-Ivanov, Andras, Mohorianu, Irina, Dalmay, Tamas and Powell, Penny P (2013) Small RNA analysis in Sindbis virus infected human HEK293 cells. PLoS One, 8 (12). ISSN 1932-6203

PDF (Donaszi-Ivanov_etal_2013_PLoSONE) - Published Version
Download (1MB) | Preview


In contrast to the defence mechanism of RNA interference (RNAi) in plants and invertebrates, its role in the innate response to virus infection of mammals is a matter of debate. Since RNAi has a well-established role in controlling infection of the alphavirus Sindbis virus (SINV) in insects, we have used this virus to investigate the role of RNAi in SINV infection of human cells.

Item Type: Article
Additional Information: © 2013 Donaszi-Ivanov et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Faculty of Science > School of Biological Sciences
Faculty of Science
Depositing User: Pure Connector
Date Deposited: 10 Jun 2014 20:28
Last Modified: 13 Jul 2021 23:48
DOI: 10.1371/journal.pone.0084070

Actions (login required)

View Item View Item