Peroxisome proliferator activated receptor ligands for the treatment of insulin resistance

Patsouris, David, Müller, Michael and Kersten, Sander (2004) Peroxisome proliferator activated receptor ligands for the treatment of insulin resistance. Current Opinion in Investigational Drugs, 5 (10). pp. 1045-50. ISSN 1472-4472

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Abstract

Peroxisome proliferator activated receptors (PPARs) are a group of ligand-activated transcription factors that play critical roles in the regulation of energy metabolism. Synthetic agonists for these receptors are used in the treatment of type 2 diabetes mellitus and dyslipidemia. Current data linking PPAR and/or PPAR ligands with the treatment of insulin resistance will be critically reviewed, with the focus on important advances over the past year.

Item Type: Article
Uncontrolled Keywords: animals,diabetes mellitus, type 2,humans,hypoglycemic agents,insulin resistance,ligands,peroxisome proliferator-activated receptors
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 07 Jul 2014 12:04
Last Modified: 14 Sep 2020 07:05
URI: https://ueaeprints.uea.ac.uk/id/eprint/47746
DOI:

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