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Murphy, Eileen F, Hooiveld, Guido J, Müller, Michael 
ORCID: https://orcid.org/0000-0002-5930-9905, Calogero, Raffaelle A and Cashman, Kevin D
(2009)
The effect of trans-10, cis-12 conjugated linoleic acid on gene expression profiles related to lipid metabolism in human intestinal-like Caco-2 cells.
Genes & Nutrition, 4 (2).
pp. 103-112.
ISSN 1555-8932
Abstract
We conducted an in-depth investigation of the effects of conjugated linoleic acid (CLA) on the expression of key metabolic genes and genes of known importance in intestinal lipid metabolism using the Caco-2 cell model. Cells were treated with 80 mumol/L of linoleic acid (control), trans-10, cis-12 CLA or cis-9, trans-11 CLA. RNA was isolated from the cells, labelled and hybridized to the Affymetrix U133 2.0 Plus arrays (n = 3). Data and functional analysis were preformed using Bioconductor. Gene ontology analysis (GO) revealed a significant enrichment (P
| Item Type: | Article |
|---|---|
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| Depositing User: | Pure Connector |
| Date Deposited: | 10 Jun 2014 21:40 |
| Last Modified: | 24 Oct 2022 06:07 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/47708 |
| DOI: | 10.1007/s12263-009-0116-7 |
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