Plasma protein profiling reveals protein clusters related to BMI and insulin levels in middle-aged overweight subjects

van Dijk, Susan J, Feskens, Edith J M, Heidema, A Geert, Bos, Marieke B, van de Rest, Ondine, Geleijnse, Johanna M, de Groot, Lisette C P G M, Müller, Michael and Afman, Lydia A (2010) Plasma protein profiling reveals protein clusters related to BMI and insulin levels in middle-aged overweight subjects. PLoS One, 5 (12). ISSN 1932-6203

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Abstract

Biomarkers that allow detection of the onset of disease are of high interest since early detection would allow intervening with lifestyle and nutritional changes before the disease is manifested and pharmacological therapy is required. Our study aimed to improve the phenotypic characterization of overweight but apparently healthy subjects and to identify new candidate profiles for early biomarkers of obesity-related diseases such as cardiovascular disease and type 2 diabetes.

Item Type: Article
Additional Information: © 2010 van Dijk et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Uncontrolled Keywords: adult,aged,biological markers,blood proteins,body mass index,cardiovascular diseases,diabetes mellitus, type 2,female,humans,insulin,male,middle aged,overweight,phenotype,proteins
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 10 Jun 2014 21:38
Last Modified: 14 Sep 2020 07:03
URI: https://ueaeprints.uea.ac.uk/id/eprint/47674
DOI: 10.1371/journal.pone.0014422

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