Measurement of teicoplanin by liquid chromatography-tandem mass spectrometry:development of a novel method

Fung, Francis H Y, Tang, Jonathan C Y, Hopkins, John P P, Dutton, John, Bailey, Lisa M and Davison, Andrew S (2012) Measurement of teicoplanin by liquid chromatography-tandem mass spectrometry:development of a novel method. Annals of Clinical Biochemistry, 49 (Pt 5). pp. 475-81. ISSN 0004-5632

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Abstract

Teicoplanin is an antibiotic used for the treatment of endocarditis, osteomyelitis, septic arthritis and methicillin-resistant Staphylococcus aureus. Teicoplanin is emerging as a suitable alternative antibiotic to vancomycin, where their trough serum levels are monitored by immunoassay routinely. This is the first report detailing the development of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for measuring teicoplanin in patients' serum.

Item Type: Article
Additional Information: Fung FH, Tang JC, Hopkins JP, Dutton JJ, Bailey LM, Davison AS. Measurement of teicoplanin by liquid chromatography-tandem mass spectrometry: development of a novel method. Ann Clin Biochem. Sep 2012;49(Pt 5):475-481.
Uncontrolled Keywords: anti-bacterial agents,blood chemical analysis,chromatography, high pressure liquid,humans,limit of detection,tandem mass spectrometry,teicoplanin
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 12 Mar 2014 13:02
Last Modified: 24 Jul 2019 19:46
URI: https://ueaeprints.uea.ac.uk/id/eprint/47568
DOI: 10.1258/acb.2012.011257

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