Age-related differences in signaling efficiency of human lens cells underpin differential wound healing response rates following cataract surgery

Dawes, Lucy Jean, Duncan, George and Wormstone, Ian Michael ORCID: https://orcid.org/0000-0002-6423-7766 (2013) Age-related differences in signaling efficiency of human lens cells underpin differential wound healing response rates following cataract surgery. Investigative Ophthalmology & Visual Science, 54 (1). pp. 333-42. ISSN 0146-0404

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Abstract

Cataract surgery is blighted by posterior capsule opacification (PCO), which is more severe and frequent in the young than the elderly (>60 years). Our aim was to understand the biological basis for these age-related differences in PCO/wound healing rates.

Item Type:	Article
Uncontrolled Keywords:	adult,aging,cataract,cataract extraction,cell proliferation,cells, cultured,disease progression,enzyme-linked immunosorbent assay,fibroblast growth factors,hepatocyte growth factor,humans,interleukins,lens, crystalline,middle aged,signal transduction,wound healing
Faculty \ School:	Faculty of Science > School of Biological Sciences Faculty of Science > School of Natural Sciences
Depositing User:	Pure Connector
Date Deposited:	28 Jan 2014 11:50
Last Modified:	24 Oct 2022 06:01
URI:	https://ueaeprints.uea.ac.uk/id/eprint/47404
DOI:	10.1167/iovs.12-10425

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