The leptin receptor Gln223Arg polymorphism (rs1137101) mediates the postprandial lipaemic response, but only in males

Jackson, Kim G, Delgado-Lista, Javier, Gill, Rosalynn, Lovegrove, Julie A, Williams, Christine M, López-Miranda, Jose and Minihane, Anne-Marie (2012) The leptin receptor Gln223Arg polymorphism (rs1137101) mediates the postprandial lipaemic response, but only in males. Atherosclerosis, 225 (1). pp. 135-41.

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Abstract

An exaggerated postprandial triacylglycerol (TAG) response is an important determinant of cardiovascular disease risk. With increased recognition of the role of leptin in systemic macronutrient metabolism, we used a candidate gene approach to examine the impact of the common leptin receptor (LEPR) Gln223Arg polymorphism (rs1137101) on postprandial lipaemia.

Item Type: Article
Additional Information: Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Uncontrolled Keywords: adult,aged,fasting,female,humans,lipids,male,metabolic syndrome x,middle aged,polymorphism, genetic,postprandial period,receptors, leptin,triglycerides
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 20 Jan 2014 14:22
Last Modified: 21 Apr 2020 22:48
URI: https://ueaeprints.uea.ac.uk/id/eprint/47341
DOI: 10.1016/j.atherosclerosis.2012.08.035

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