Visual function and white matter microstructure in very-low-birth-weight (VLBW) adolescents--a DTI study

Lindqvist, Susanne, Skranes, Jon, Eikenes, Live, Haraldseth, Olav, Vik, Torstein, Brubakk, Ann-Mari and Vangberg, Torgil Riise (2011) Visual function and white matter microstructure in very-low-birth-weight (VLBW) adolescents--a DTI study. Vision Research, 51 (18). pp. 2063-70. ISSN 1878-5646

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Abstract

Premature birth is associated with visual impairments, due to both cerebral and ocular pathology. This study examined the relationship between cerebral white matter microstructure, evaluated by diffusion tensor imaging (DTI), and visual function, in 30 preterm born adolescents with very low birth weight (VLBW=birth weight⩽1500g) and an age-matched group of 45 term born controls. Visual acuity correlated positively with fractional anisotropy (FA) in corpus callosum and in frontal white matter areas in the VLBW participants, but not in the control participants. Callosal visual connections may play a more important role in the development of good visual acuity than previously acknowledged in preterm born children.

Item Type: Article
Additional Information: Copyright © 2011 Elsevier Ltd. All rights reserved.
Uncontrolled Keywords: adolescent,brain,diffusion tensor imaging,female,humans,infant, newborn,infant, very low birth weight,male,regression analysis,vision, ocular,visual acuity
Depositing User: Pure Connector
Date Deposited: 06 Aug 2014 12:16
Last Modified: 21 Apr 2020 22:36
URI: https://ueaeprints.uea.ac.uk/id/eprint/46591
DOI: 10.1016/j.visres.2011.08.002

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