Systematic Review of Hirudin in Acute Coronary Syndromes and Percutaneous Coronary Intervention

Perez De Arenaza, Diego, Flather, Marcus D., Shibata, Marcelo C. and Bakhai, Ameet (2001) Systematic Review of Hirudin in Acute Coronary Syndromes and Percutaneous Coronary Intervention. Current Interventional Cardiology Reports, 3 (2). pp. 156-162. ISSN 1523-3839

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Abstract

Thrombin plays a key role in the pathogenesis of acute coronary syndromes because it is a potent platelet agonist and converts fibrinogen to fibrin. Hirudin is a powerful, direct, and specific antithrombin agent that can be used in many therapeutic scenarios in which heparin is routinely used. In this systemic review, we summarize evidence from randomized clinical trials evaluating the benefits and risks of recombinant hirudin for the treatment of acute coronary syndromes and patients undergoing percutaneous coronary intervention.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 20 Jan 2014 16:18
Last Modified: 12 Sep 2020 23:35
URI: https://ueaeprints.uea.ac.uk/id/eprint/46309
DOI:

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