An analysis of mortality rates with dual-antiplatelet therapy in the primary prevention population of the CHARISMA trial

Wang, Thomas H, Bhatt, Deepak L, Fox, Keith A A, Steinhubl, Steven R, Brennan, Danielle M, Hacke, Werner, Mak, Koon-Hou, Pearson, Thomas A, Boden, William E, Steg, P Gabriel, Flather, Marcus D, Montalescot, Gilles and Topol, Eric J and CHARISMA Investigators (2007) An analysis of mortality rates with dual-antiplatelet therapy in the primary prevention population of the CHARISMA trial. European Heart Journal, 28 (18). pp. 2200-7. ISSN 0195-668X

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Abstract

To examine the unanticipated, excess mortality observed in patients randomized to clopidogrel and aspirin vs. aspirin alone in the prespecified 'asymptomatic' subgroup of CHARISMA, we investigated whether dual-antiplatelet therapy may be associated with adverse cardiovascular (CV) events in a primary prevention population.

Item Type:	Article
Uncontrolled Keywords:	aged,aspirin,atherosclerosis,cardiovascular diseases,disease-free survival,drug therapy, combination,epidemiologic methods,female,hemorrhage,humans,male,middle aged,myocardial infarction,platelet aggregation inhibitors,stroke,ticlopidine,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023)
Depositing User:	Pure Connector
Date Deposited:	06 Jan 2014 15:18
Last Modified:	03 Nov 2022 15:35
URI:	https://ueaeprints.uea.ac.uk/id/eprint/46271
DOI:	10.1093/eurheartj/ehm274

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