Dietary phosphate modulates atherogenesis and insulin resistance in apolipoprotein E knockout mice--brief report

Ellam, Timothy, Wilkie, Martin, Chamberlain, Janet, Crossman, David, Eastell, Richard, Francis, Sheila and Chico, Timothy J A (2011) Dietary phosphate modulates atherogenesis and insulin resistance in apolipoprotein E knockout mice--brief report. Arteriosclerosis, Thrombosis, and Vascular Biology, 31 (9). pp. 1988-90. ISSN 1079-5642

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Abstract

Epidemiological studies link higher serum phosphate and the phosphatonin fibroblast growth factor 23 with cardiovascular events and atheroma, and they link lower serum phosphate with insulin resistance and the metabolic syndrome. We investigated whether manipulating dietary phosphate influences atherogenesis or insulin sensitivity in mice.

Item Type:	Article
Uncontrolled Keywords:	adiposity,animals,apolipoproteins e,atherosclerosis,fatty liver,insulin resistance,male,mice,mice, knockout,phosphates
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit
Depositing User:	Pure Connector
Date Deposited:	20 Jan 2014 16:04
Last Modified:	24 Oct 2022 05:34
URI:	https://ueaeprints.uea.ac.uk/id/eprint/46189
DOI:	10.1161/ATVBAHA.111.231001

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