Altered DNA methylation profile in idiopathic pulmonary fibrosis

Sanders, Yan Y, Ambalavanan, Namasivayam, Halloran, Brian, Zhang, Xiangyu, Liu, Hui, Crossman, David K, Bray, Molly, Zhang, Kui, Thannickal, Victor J and Hagood, James S (2012) Altered DNA methylation profile in idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine, 186 (6). pp. 525-35. ISSN 1073-449X

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Abstract

DNA methylation is an important epigenetic mechanism, which often occurs in response to environmental stimuli and is crucial in regulating gene expression. It is likely that epigenetic alterations contribute to pathogenesis in idiopathic pulmonary fibrosis (IPF).

Item Type: Article
Uncontrolled Keywords: amidohydrolases,biopsy, needle,blotting, western,claudin-5,dna methylation,dna modification methylases,down-regulation,gene expression profiling,gene expression regulation,humans,idiopathic pulmonary fibrosis,immunohistochemistry,rna, messenger,real-time polymerase chain reaction,sampling studies,sensitivity and specificity,tissue culture techniques
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 06 Jan 2014 15:16
Last Modified: 21 Apr 2020 22:32
URI: https://ueaeprints.uea.ac.uk/id/eprint/46180
DOI: 10.1164/rccm.201201-0077OC

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