Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer:a prospective, two-stage study

Olmos, David, Brewer, Daniel, Clark, Jeremy, Danila, Daniel C, Parker, Chris, Attard, Gerhardt, Fleisher, Martin, Reid, Alison Hm, Castro, Elena, Sandhu, Shahneen K, Barwell, Lorraine, Oommen, Nikhil Babu, Carreira, Suzanne, Drake, Charles G, Jones, Robert, Cooper, Colin S, Scher, Howard I and de Bono, Johann S (2012) Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer:a prospective, two-stage study. The Lancet Oncology, 13 (11). pp. 1114-24. ISSN 1470-2045

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Abstract

Biomarkers are urgently needed to dissect the heterogeneity of prostate cancer between patients to improve treatment and accelerate drug development. We analysed blood mRNA expression arrays to identify patients with metastatic castration-resistant prostate cancer with poorer outcome.

Item Type: Article
Additional Information: Copyright © 2012 Elsevier Ltd. All rights reserved.
Uncontrolled Keywords: aged,aged 80 and over,castration,gene expression profiling,gene expression regulation, neoplastic,humans,inflammation,male,middle aged,neoplasm grading,neoplasm metastasis,neoplasm staging,prognosis,prospective studies,prostatic neoplasms,messenger rna,survival analysis,tumor markers (biological)
Faculty \ School: Faculty of Science > School of Biological Sciences
Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 06 Jan 2014 14:16
Last Modified: 21 Apr 2020 22:31
URI: https://ueaeprints.uea.ac.uk/id/eprint/46120
DOI: 10.1016/S1470-2045(12)70372-8

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