Statin use is associated with reduced risk of histologic subtypes of esophageal cancer: A nested case-control analysis

Alexandre, Leo, Clark, Allan B. ORCID: https://orcid.org/0000-0003-2965-8941, Bhutta, Hina Y., Holt, Sean, Lewis, Michael P. N. and Hart, Andrew R. (2014) Statin use is associated with reduced risk of histologic subtypes of esophageal cancer: A nested case-control analysis. Gastroenterology, 146 (3). 661–668. ISSN 0016-5085

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Abstract

Most patients with esophageal adenocarcinoma (EAC) or squamous cell cancer (ESCC) present with advanced, incurable disease. Statins have reported anti-carcinogenic effects and may be chemoprotective. We investigated the association between regular use of statins and the main histologic subtypes of esophageal malignancy (EAC, esophagogastric junctional adenocarcinoma [EGJA], and ESCC) in the UK general population.

Item Type:	Article
Additional Information:	Copyright © 2013 AGA Institute. Published by Elsevier Inc. All rights reserved.
Uncontrolled Keywords:	esophageal cancer,statins,aetiology,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Health Services and Primary Care Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Centres > Population Health Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User:	Pure Connector
Date Deposited:	20 Jan 2014 15:54
Last Modified:	06 Jun 2024 14:43
URI:	https://ueaeprints.uea.ac.uk/id/eprint/46092
DOI:	10.1053/j.gastro.2013.11.046

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