Statin use is associated with reduced risk of histologic subtypes of esophageal cancer: A nested case-control analysis

Alexandre, Leo, Clark, Allan B., Bhutta, Hina Y., Holt, Sean, Lewis, Michael P. N. and Hart, Andrew R. (2014) Statin use is associated with reduced risk of histologic subtypes of esophageal cancer: A nested case-control analysis. Gastroenterology, 146 (3). 661–668. ISSN 0016-5085

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Abstract

Most patients with esophageal adenocarcinoma (EAC) or squamous cell cancer (ESCC) present with advanced, incurable disease. Statins have reported anti-carcinogenic effects and may be chemoprotective. We investigated the association between regular use of statins and the main histologic subtypes of esophageal malignancy (EAC, esophagogastric junctional adenocarcinoma [EGJA], and ESCC) in the UK general population.

Item Type:	Article
Additional Information:	Copyright © 2013 AGA Institute. Published by Elsevier Inc. All rights reserved.
Uncontrolled Keywords:	esophageal cancer,statins,aetiology,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Health Services and Primary Care Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Centres > Population Health Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health Faculty of Science > Research Groups > Statistics
Depositing User:	Pure Connector
Date Deposited:	20 Jan 2014 15:54
Last Modified:	28 Mar 2025 05:39
URI:	https://ueaeprints.uea.ac.uk/id/eprint/46092
DOI:	10.1053/j.gastro.2013.11.046

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