Catch-up growth following intra-uterine growth-restriction programmes an insulin-resistant phenotype in adipose tissue

Berends, L M, Fernandez-Twinn, D S, Martin-Gronert, M S, Cripps, R L and Ozanne, S E (2013) Catch-up growth following intra-uterine growth-restriction programmes an insulin-resistant phenotype in adipose tissue. International Journal of Obesity, 37 (8). pp. 1051-1057. ISSN 1476-5497

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Abstract

It is now widely accepted that the early-life nutritional environment is important in determining susceptibility to metabolic diseases. In particular, intra-uterine growth restriction followed by accelerated postnatal growth is associated with an increased risk of obesity, type-2 diabetes and other features of the metabolic syndrome. The mechanisms underlying these observations are not fully understood.

Item Type: Article
Uncontrolled Keywords: developmental programming,maternal under-nutrition,catch-up growth,adipose tissue,insulin resistance,type-2 diabetes
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 04 Nov 2013 22:10
Last Modified: 21 Apr 2020 22:08
URI: https://ueaeprints.uea.ac.uk/id/eprint/44223
DOI: 10.1038/ijo.2012.196

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