Silver cations fold i-motif at neutral pH

Day, Henry A., Huguin, Camille and Waller, Zoe A. E. (2013) Silver cations fold i-motif at neutral pH. Chemical Communications, 49 (70). pp. 7696-7698. ISSN 1359-7345

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Abstract

i-Motif DNA structures have previously been utilised for many different nanotechnological applications, but all have used acidic conditions to fold the DNA. Herein we describe the use of silver cations to fold an i-motif forming DNA sequence at physiological pH. Subsequent DNA unfolding can be achieved by chelation with cysteine.

Item Type:	Article
Faculty \ School:	Faculty of Science Faculty of Science > School of Pharmacy
UEA Research Groups:	Faculty of Science > Research Groups > Chemical Biology and Medicinal Chemistry (former - to 2021) Faculty of Science > Research Groups > Medicinal Chemistry (former - to 2017)
Depositing User:	Pure Connector
Date Deposited:	20 Aug 2013 05:29
Last Modified:	01 Aug 2023 02:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/43144
DOI:	10.1039/c3cc43495h

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