Using next generation sequencing to tackle non-typhoidal Salmonella infections

Wain, John, Keddy, Karen H, Hendriksen, Rene S and Rubino, Salvatore (2013) Using next generation sequencing to tackle non-typhoidal Salmonella infections. Journal of Infection in Developing Countries, 7 (01). pp. 1-5. ISSN 1972-2680

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Abstract

The publication of studies using next generation sequencing to analyse large numbers of bacterial isolates from global epidemics is transforming microbiology, epidemiology and public health. The emergence of multidrug resistant Salmonella Typhimurium ST313 is one example. While the epidemiology in Africa appears to be human-to-human spread and the association with invasive disease almost absolute, more needs to be done to exclude the possibility of animal reservoirs and to transfer the ability to track all Salmonella infections to the laboratories in the front line. In this mini-review we summarise what is currently known about non-typhoidal Salmonella in sub-Saharan Africa and discuss some of the issues which remain.

Item Type: Article
Uncontrolled Keywords: africa south of the sahara,animals,anti-bacterial agents,dna, bacterial,disease reservoirs,drug resistance, multiple, bacterial,humans,salmonella infections,salmonella infections, animal,salmonella typhimurium,sequence analysis, dna
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 09 Jul 2013 08:54
Last Modified: 21 Apr 2020 21:48
URI: https://ueaeprints.uea.ac.uk/id/eprint/42867
DOI: 10.3855/jidc.3080

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