Characterization of -Lactamase and Porin Mutants of Enterobacteriaceae Selected with Ceftaroline + Avibactam (NXL104).

Livermore, David M, Mushtaq, Shazad, Barker, Kevin, Hope, Russell, Warner, Marina and Woodford, Neil (2012) Characterization of -Lactamase and Porin Mutants of Enterobacteriaceae Selected with Ceftaroline + Avibactam (NXL104). Journal of Antimicrobial Chemotherapy, 67 (6). pp. 1354-1358. ISSN 0305-7453

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Abstract

Ceftaroline + avibactam (NXL104) is a novel inhibitor combination active against Enterobacteriaceae with class A and C β-lactamases. We investigated its risk of mutational resistance.

Item Type: Article
Uncontrolled Keywords: anti-bacterial agents,azabicyclo compounds,cephalosporins,drug resistance, bacterial,enterobacteriaceae,genomic instability,microbial sensitivity tests,mutant proteins,phenotype,porins,selection, genetic,beta-lactamases
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Related URLs:
Depositing User: Sophie Buckingham
Date Deposited: 05 Mar 2013 10:55
Last Modified: 21 Apr 2020 16:24
URI: https://ueaeprints.uea.ac.uk/id/eprint/41712
DOI: 10.1093/jac/dks079

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