Breakthrough in cachexia treatment through a novel selective androgen receptor modulator?!

Thum, Thomas and Springer, Jochen (2011) Breakthrough in cachexia treatment through a novel selective androgen receptor modulator?! Journal of Cachexia, Sarcopenia and Muscle, 2 (3). pp. 121-123. ISSN 2190-5991

Full text not available from this repository.

Abstract

Cachexia, and particularly the loss of metabolically active lean tissue, leads to increased morbidity and mortality in affected patients. An impairment of strength and functional status is usually associated with cachexia. A variety of anabolic and appetite-stimulating agents have been studied in patients with cachexia caused by various underlying diseases. Overall, these studies have demonstrated that treatment can increase body weight and/or lean body mass. However, these therapies may have severe side effects, particularly when utilizing testosterone and related anabolic steroids targeting the androgen receptor. These side effects include cardiovascular problems, prostate hyperplasia and cancer in men, as well as virilization in women.

Item Type:	Article
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Depositing User:	Jochen Springer
Date Deposited:	17 Apr 2013 21:44
Last Modified:	22 Oct 2022 05:09
URI:	https://ueaeprints.uea.ac.uk/id/eprint/41648
DOI:	10.1007/s13539-011-0040-8

Actions (login required)

View Item