Ursodeoxycholic acid treatment in a rat model of cancer cachexia

Tschirner, A, von Haehling, S, Palus, S, Doehner, W, Anker, SD and Springer, J (2012) Ursodeoxycholic acid treatment in a rat model of cancer cachexia. Journal of Cachexia, Sarcopenia and Muscle, 3 (1). pp. 31-36. ISSN 2190-5991

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UDCA treatment in the Yoshida hepatoma model showed a trend towards attenuation of tissue loss in animals with progressive weight loss in cancer cachexia. Tumor growth and activity indicators were not altered. Both doses of UDCA tended to reduce the mortality rates in tumor-bearing animals. Larger studies with longer follow-up are required to verify these findings.

Item Type: Article
Additional Information: © 2012 The Authors. Published by John Wiley & Sons Ltd on behalf of the Society on Sarcopenia, Cachexia and Wasting Disorders This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Uncontrolled Keywords: sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Depositing User: Jochen Springer
Date Deposited: 01 May 2013 10:09
Last Modified: 22 Oct 2022 21:31
URI: https://ueaeprints.uea.ac.uk/id/eprint/41642
DOI: 10.1007/s13539-011-0044-4

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