Large scale population-based study shows no association between common polymorphisms of the TGFBI gene and BMD in women

McGuigan, Fiona E. A., Macdonald, Helen M., Bassiti, Amelia, Farmer, Rosemary, Bear, Stuart, Stewart, Alison, Black, Alison, Fraser, William D., Welsh, Findlay, Reid, David M. and Ralston, Stuart H. (2007) Large scale population-based study shows no association between common polymorphisms of the TGFBI gene and BMD in women. Journal of Bone and Mineral Research, 22 (2). pp. 195-202. ISSN 1523-4681

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Abstract

The TGFB1 gene is a strong functional candidate for regulating genetic susceptibility to osteoporosis. We studied five common polymorphisms of TGFB1 in relation to osteoporosis-related phenotypes in a population-based cohort of 2975 British women, but found no significant association with bone mass, bone loss, bone markers, or fracture.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User:	Users 2731 not found.
Date Deposited:	05 Feb 2013 10:47
Last Modified:	25 Apr 2025 00:01
URI:	https://ueaeprints.uea.ac.uk/id/eprint/41090
DOI:	10.1359/jbmr.061016

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