Radial artery pulse wave analysis for non-invasive assessment of coronary artery disease

Kotecha, Dipak, New, Gishel, Collins, Peter, Eccleston, David, Krum, Henry, Pepper, John and Flather, Marcus D. (2013) Radial artery pulse wave analysis for non-invasive assessment of coronary artery disease. International Journal of Cardiology, 167 (3). 917–924. ISSN 1874-1754

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Abstract

BACKGROUND: Angiographically-normal coronary arteries are reported in 10-20% of patients undergoing diagnostic coronary angiography despite screening with risk factors and functional tests. We sought to validate and determine the clinical value of radial artery pulse wave analysis (PWA), a simple, quick and non-invasive marker of central artery stiffness and define its ability to predict coronary artery disease in high-risk patients. MATERIALS AND METHODS: 531 consecutive patients referred for elective coronary angiography, irrespective of previous co-morbidity, were assessed in a prospective, multicenter observational study [the Alternative Risk Markers in Coronary Artery Disease (ARM-CAD) study]. RESULTS: Mean age was 65±11years, 33% were women, 18% had impaired left-ventricular function and 22% a prior myocardial infarction. Angiography demonstrated normal coronary arteries in 20% of participants. The only independent associations with this outcome were younger age, female gender, absence of diabetes and PWA-derived central augmentation pressure

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Users 2731 not found.
Date Deposited: 04 Jul 2012 09:16
Last Modified: 11 May 2020 23:42
URI: https://ueaeprints.uea.ac.uk/id/eprint/39051
DOI: 10.1016/j.ijcard.2012.03.098

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