Shape and Polarity in Co-crystal Formation: Database Analysis and Experimental Validation

Fabian, L. and Frišcic, T. (2012) Shape and Polarity in Co-crystal Formation: Database Analysis and Experimental Validation. In: Pharmaceutical Salts and Co-crystals. RSC Drug Discovery Series (16). Royal Society of Chemistry, pp. 89-109. ISBN 978-1-84973-158-4

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Abstract

Supramolecular synthons provide the most important and successful approach to the rational design of co-crystals. Yet, the relatively low success rate of co-crystal screening experiments demonstrates that the availability of appropriate synthons is only one of many factors that influence co-crystallisation. The aim of our work was to identify other factors and to use them in developing design strategies that are complementary to supramolecular synthons.

Item Type:	Book Section
Faculty \ School:	Faculty of Science > School of Pharmacy
Depositing User:	Laszlo Fabian
Date Deposited:	08 May 2013 14:30
Last Modified:	08 Nov 2022 12:31
URI:	https://ueaeprints.uea.ac.uk/id/eprint/37456
DOI:	10.1039/9781849733502-00089

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