Oxidation of dimethylsulfide to tetrathionate by Methylophaga thiooxidams: a new link in the sulphur cycle

Boden, Rich, Kelly, Donovan P., Murrell, J. Colin and Schaefer, Hendrik (2010) Oxidation of dimethylsulfide to tetrathionate by Methylophaga thiooxidams: a new link in the sulphur cycle. Environmental Microbiology, 12 (10). pp. 2688-2699. ISSN 1462-2920

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A new pathway of dimethylsulfide (DMS) metabolism was identified in a novel species of Gammaproteobacteria, Methylophaga thiooxidans sp. nov., in which tetrathionate (S4O62−) was the end-product of DMS oxidation. Inhibitor evidence indicated that DMS degradation was initiated by demethylation, catalysed by a corrinoid demethylase. Thiosulfate was an intermediate, which was oxidized to tetrathionate by a cytochrome-linked thiosulfate dehydrogenase. Thiosulfate oxidation was coupled to ATP synthesis, and M. thiooxidans could also use exogenous thiosulfate as an energy source during chemolithoheterotrophic growth on DMS or methanol. Cultures grown on a variety of substrates oxidized thiosulfate, indicating that thiosulfate oxidation was constitutive. The observations have relevance to interactions among sulfur-metabolizing bacteria in the marine environment. The production of tetrathionate from an organosulfur precursor is previously undocumented and represents a potential step in the biogeochemical sulfur cycle, providing a ‘shunt’ across the cycle.

Item Type: Article
Faculty \ School: Faculty of Science > School of Environmental Sciences
UEA Research Groups: Faculty of Science > Research Centres > Centre for Ecology, Evolution and Conservation
Faculty of Science > Research Groups > Environmental Biology
Faculty of Science > Research Groups > Resources, Sustainability and Governance (former - to 2018)
Faculty of Science > Research Groups > Marine and Atmospheric Sciences (former - to 2017)
Depositing User: Users 2731 not found.
Date Deposited: 24 Jan 2012 14:44
Last Modified: 14 Aug 2023 09:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/36443
DOI: 10.1111/j.1462-2920.2010.02238.x

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