A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes

Gubbay, John, Collignon, Jérôme, Koopman, Peter, Capel, Blanche, Economou, Androulla, Munsterberg, Andrea, Vivian, Nigel, Goodfellow, Peter and Lovell-Badge, Robin (1990) A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature, 346 (6281). pp. 245-250. ISSN 0028-0836

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Abstract

A gene mapping to the sex-determining region of the mouse Y chromosome is deleted in a line of XY female mice mutant for Tdy, and is expressed at a stage during male gonadal development consistent with its having a role in testis determination. This gene is a member of a new family of at least five mouse genes, related by an amino-acid motif showing homology to other known or putative DNA-binding domains.

Item Type: Article
Faculty \ School: Faculty of Science > School of Biological Sciences
Depositing User: Users 2731 not found.
Date Deposited: 13 Sep 2011 10:44
Last Modified: 21 Apr 2020 21:39
URI: https://ueaeprints.uea.ac.uk/id/eprint/34762
DOI: 10.1038/346245a0

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