A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes

Gubbay, John, Collignon, Jérôme, Koopman, Peter, Capel, Blanche, Economou, Androulla, Munsterberg, Andrea ORCID: https://orcid.org/0000-0002-4577-4240, Vivian, Nigel, Goodfellow, Peter and Lovell-Badge, Robin (1990) A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature, 346 (6281). pp. 245-250. ISSN 0028-0836

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Abstract

A gene mapping to the sex-determining region of the mouse Y chromosome is deleted in a line of XY female mice mutant for Tdy, and is expressed at a stage during male gonadal development consistent with its having a role in testis determination. This gene is a member of a new family of at least five mouse genes, related by an amino-acid motif showing homology to other known or putative DNA-binding domains.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Biological Sciences
Depositing User:	Users 2731 not found.
Date Deposited:	13 Sep 2011 10:44
Last Modified:	22 Apr 2023 23:59
URI:	https://ueaeprints.uea.ac.uk/id/eprint/34762
DOI:	10.1038/346245a0

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