The threat from the pink corner

Livermore, David M (2003) The threat from the pink corner. Annals of Medicine, 35 (4). pp. 226-234. ISSN 0785-3890

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In terms of numbers of isolates, the greatest present resistance problems arise with gram-positive pathogens (which stain purple/black in Gram's method), especially methicillin-resistant Staphylococcus aureus (MRSA). But, is the MRSA problem -- by its size -- blinding us to something ultimately more dangerous: the slow emergence of gram-negative pathogens (which stain pink) with resistance to all reliable antibiotics? Although presently rare, 'pan-resistant' gram-negative bacteria -- predominantly strains of Pseudomonas aeruginosa and Acinetobacter baumannii- have more comprehensive resistance than any gram-positive pathogen. They already pose treatment problems in compromised hospital patients, especially in specialist units, as well in particular groups, such as cystic fibrosis patents. Disturbingly, there is a near-total lack of developmental antibiotics active against gram-negative pathogens.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Rhiannon Harvey
Date Deposited: 11 Jul 2011 11:25
Last Modified: 08 Mar 2023 11:31
DOI: 10.1080/07853890310001609

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