Activity of daptomycin against multi-resistant Gram-positive bacteria including enterococci and Staphylococcus aureus resistant to linezolid

Johnson, A, Mushtaq, S, Warner, M and Livermore, DM (2004) Activity of daptomycin against multi-resistant Gram-positive bacteria including enterococci and Staphylococcus aureus resistant to linezolid. International Journal of Antimicrobial Agents, 24 (4). pp. 315-319. ISSN 1872-7913

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Abstract

The activity of daptomycin was assessed against 545 isolates of Gram-positive bacteria including enterococci, coagulase-positive and -negative staphylococci, ß-haemolytic streptococci, viridans streptococci and coryneforms. The panel of isolates was biased towards those with resistance to first-line antimicrobial agents and included linezolid-resistant enterococci and Staphylococcus aureus. MICs of daptomycin were =1 mg/l for all the staphylococci, streptococci, and coryneforms, except for two isolates of Corynebacterium aquaticum, for which MICs were 8 mg/l. Daptomycin MICs were =2 and =4 mg/l for Enterococcus faecalis and Enterococcus faecium, respectively.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Rhiannon Harvey
Date Deposited: 11 Jul 2011 11:06
Last Modified: 21 Apr 2020 20:12
URI: https://ueaeprints.uea.ac.uk/id/eprint/33488
DOI: 10.1016/j.ijantimicag.2004.04.006

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