Comparison of BD Phoenix, Vitek 2, and MicroScan Automated Systems for Detection and Inference of Mechanisms Responsible for Carbapenem Resistance in Enterobacteriaceae

Woodford, Neil, Eastaway, Anne T., Ford, Michael, Leanord, Alistair, Keane, Chloe, Quayle, Reinhard M., Steer, Jane A., Zhang, Jiancheng and Livermore, Daivd M. (2010) Comparison of BD Phoenix, Vitek 2, and MicroScan Automated Systems for Detection and Inference of Mechanisms Responsible for Carbapenem Resistance in Enterobacteriaceae. Journal of Clinical Microbiology, 48 (8). pp. 2999-3002. ISSN 0095-1137

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Abstract

We assessed the ability of three commercial systems to infer carbapenem resistance mechanisms in 39 carbapenemase-producing and 16 other carbapenem-resistant Enterobacteriaceae. The sensitivity/specificity values for “flagging” a likely carbapenemase were 100%/0% (BD Phoenix), 82 to 85%/6 to 19% (MicroScan), and 74%/38% (Vitek 2), respectively. OXA-48 producers were poorly detected, but all systems reliably detected isolates with KPC and most with metallo-carbapenemases.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Rhiannon Harvey
Date Deposited: 05 Jul 2011 11:00
Last Modified: 21 Apr 2020 17:00
URI: https://ueaeprints.uea.ac.uk/id/eprint/33347
DOI: 10.1128/JCM.00341-10

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