The highly diastereoselective synthesis of oxazolidines derived from ketones and pseudoephedrine or ephedrine

Buckley, Benjamin R., Bulman Page, Philip C., Edgar, Mark, Elsegood, Mark R. J., Hayman, Colin M., Heaney, Harry, Rassias, Gerasimos A., Talib, Salem A., Liddle, John, Readshaw, Simon A. and Seaman, Christopher J. (2005) The highly diastereoselective synthesis of oxazolidines derived from ketones and pseudoephedrine or ephedrine. Synlett (6). pp. 971-975. ISSN 0936-5214

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Abstract

2,2-Dialkyl-3,4-dimethyl-5-phenyloxazolidines and 2-alkyl-2-aryl-3,4-dimethyl-5-phenyloxazolidines are formed with high diastereoselectivity from ketones and pseudoephedrine or ephedrine in the presence of scandium triflate and 4 A molecular sieves.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Chemistry (former - to 2024)
UEA Research Groups:	Faculty of Science > Research Groups > Chemistry of Materials and Catalysis Faculty of Science > Research Groups > Synthetic Chemistry (former - to 2017)
Depositing User:	Rachel Smith
Date Deposited:	20 Jun 2011 15:40
Last Modified:	28 Mar 2025 04:10
URI:	https://ueaeprints.uea.ac.uk/id/eprint/32861
DOI:	10.1055/s-2005-864824

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