A short preparation of an advanced intermediate for lactacystin synthesis: The complete carbon skeleton of clasto-lactacystin dihydroxyacid

Bulman Page, P. C. B., Leach, D. C., Hayman, C. M., Hamzah, A. S., Allin, S. M. and McKee, V. (2003) A short preparation of an advanced intermediate for lactacystin synthesis: The complete carbon skeleton of clasto-lactacystin dihydroxyacid. Synlett (7). pp. 1025-1027. ISSN 0936-5214

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Abstract

An advanced intermediate 22 for lactacystin Synthesis, containing the full carbon skeleton of the pyrrolidinone component, has been achieved in four steps from a protected glycine ester.

Item Type:	Article
Uncontrolled Keywords:	proteasome inhibitors,dieckmann,lactacystin,route,analogs,clasto-lactacystin,tools,d-glucose,efficient,beta-lactone,acylation,(+)-lactacystin
Faculty \ School:	Faculty of Science > School of Chemistry
Depositing User:	Rachel Smith
Date Deposited:	21 Jun 2011 10:16
Last Modified:	24 Oct 2022 02:53
URI:	https://ueaeprints.uea.ac.uk/id/eprint/32849
DOI:

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