A short preparation of an advanced intermediate for lactacystin synthesis: The complete carbon skeleton of clasto-lactacystin dihydroxyacid

Bulman Page, P. C. B., Leach, D. C., Hayman, C. M., Hamzah, A. S., Allin, S. M. and McKee, V. (2003) A short preparation of an advanced intermediate for lactacystin synthesis: The complete carbon skeleton of clasto-lactacystin dihydroxyacid. Synlett (7). pp. 1025-1027. ISSN 0936-5214

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Abstract

An advanced intermediate 22 for lactacystin Synthesis, containing the full carbon skeleton of the pyrrolidinone component, has been achieved in four steps from a protected glycine ester.

Item Type: Article
Uncontrolled Keywords: proteasome inhibitors,dieckmann,lactacystin,route,analogs,clasto-lactacystin,tools,d-glucose,efficient,beta-lactone,acylation,(+)-lactacystin
Faculty \ School: Faculty of Science > School of Chemistry
Depositing User: Rachel Smith
Date Deposited: 21 Jun 2011 10:16
Last Modified: 21 Apr 2020 20:29
URI: https://ueaeprints.uea.ac.uk/id/eprint/32849
DOI:

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