Regional migratory osteoporosis: a review illustrated by five cases

Toms, A. P., Marshall, T. J., Becker, E., Donell, S. T., Lobo-Mueller, E. M. and Barker, T. (2005) Regional migratory osteoporosis: a review illustrated by five cases. Clinical Radiology, 60 (4). pp. 425-438. ISSN 1365-229X

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Regional migratory osteoporosis is an uncommon self-limiting disease characterized by an arthralgia which migrates between the weight-bearing joints of the lower limb. The radiological features of the disease obtained by conventional radiography, CT, MRI and radionuclide scintigraphy are illustrated by means of five case reports. These range from the most common presentation of sequential, proximal to distal spread in the lower limb to the rare intra-articular form, and disease involving the axial skeleton is also recognized. Clinical and radiographical features often overlap with those of diseases such as transient osteoporosis of the hip and transient bone marrow oedema syndrome, which is reflected in confusing terminology. Histological sampling is usually unnecessary; the radiological features are characteristic and the histological findings are not specific. Regional migratory osteoporosis is associated with systemic osteoporosis. This association is probably under-recognized, and has implications for the pathophysiology of the disease and for treatment.

Item Type: Article
Uncontrolled Keywords: adult,ankle,bone marrow,bone marrow diseases,bone and bones,edema,female,femur,humans,leg,magnetic resonance imaging,male,middle aged,osteoporosis,pelvis,tomography, x-ray computed
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Rhiannon Harvey
Date Deposited: 15 Jun 2011 15:25
Last Modified: 24 Oct 2022 02:11
DOI: 10.1016/j.crad.2004.07.002

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