Silver-sensitive enantioselectivity in asymmetric Heck reactions

McDermott, Michael C., Stephenson, G. Richard and Walkington, Andrew J. (2007) Silver-sensitive enantioselectivity in asymmetric Heck reactions. Synlett (1). pp. 51-54. ISSN 0936-5214

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Abstract

Amine- and pure Ag(I)-promoted asymmetric Heck cyclisations of 2-iodobut-2-enanilide 1 both gave the oxindole product (R)-(+)-2 in relatively low ee but the partial reduction of the silver salt promoted a substantially more stereocontrolled route to (S)-(-)-2 in a reaction in which the use of Strem Atg(3)PO(4) gave the R-product and Aldrich Ag3PO4 gave the S-product.

Item Type: Article
Additional Information: McDermott, Michael C. Stephenson, G. Richard Walkington, Andrew J.
Faculty \ School: Faculty of Science > School of Chemistry
Depositing User: Rachel Smith
Date Deposited: 08 Jun 2011 10:48
Last Modified: 21 Apr 2020 19:28
URI: https://ueaeprints.uea.ac.uk/id/eprint/32011
DOI: 10.1055/s-2006-958447

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