Trans fatty acids and weight gain

Thompson, A. K., Minihane, A.-M. and Williams, C. M. (2011) Trans fatty acids and weight gain. International Journal of Obesity, 35 (3). pp. 315-324. ISSN 0307-0565

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Abstract

Increasing rates of obesity have stimulated research into possible contributing factors, including specific dietary components such as trans fatty acids (TFAs). This review considers the evidence for an association between TFA intake and weight gain. It concludes that there is limited but consistent evidence from epidemiological studies, and from a primate model, that increased TFA consumption may result in a small additional weight gain. Data from a long-term study in a primate model suggest that TFA may have a greater adipogenic effect than cis monounsaturated fatty acids; however, there are currently inadequate mechanistic data to provide a comprehensive and plausible explanation for any such metabolic differences between the types of fatty acids.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Depositing User:	Rhiannon Harvey
Date Deposited:	31 May 2011 13:28
Last Modified:	28 Mar 2025 02:46
URI:	https://ueaeprints.uea.ac.uk/id/eprint/31583
DOI:	10.1038/ijo.2010.141

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