Combining contemporary and ancient DNA in population genetic and phylogeographical studies

Navascues, Miguel, Depaulis, Frantz and Emerson, Brent C. (2010) Combining contemporary and ancient DNA in population genetic and phylogeographical studies. Molecular Ecology Resources, 10 (5). pp. 760-772. ISSN 1755-0998

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The analysis of ancient DNA in a population genetic or phylogeographical framework is an emerging field, as traditional analytical tools were largely developed for the purpose of analysing data sampled from a single time point. Markov chain Monte Carlo approaches have been successfully developed for the analysis of heterochronous sequence data from closed panmictic populations. However, attributing genetic differences between temporal samples to mutational events between time points requires the consideration of other factors that may also result in genetic differentiation. Geographical effects are an obvious factor for species exhibiting geographical structuring of genetic variation. The departure from a closed panmictic model require researchers to either exploit software developed for the analysis of isochronous data, take advantage of simulation approaches using algorithms developed for heterochronous data, or explore approximate Bayesian computation. Here, we review statistical approaches employed and available software for the joint analysis of ancient and modern DNA, and where appropriate we suggest how these may be further developed.

Item Type: Article
Faculty \ School: Faculty of Science > School of Biological Sciences
UEA Research Groups: Faculty of Science > Research Groups > Organisms and the Environment
Depositing User: Users 2731 not found.
Date Deposited: 24 May 2011 11:36
Last Modified: 15 May 2023 23:55
DOI: 10.1111/j.1755-0998.2010.02895.x

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