New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity of an unusual NRPS

Ragab, Amany E., Gruschow, Sabine, Rackham, Emma J. and Goss, Rebecca J. M. (2010) New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity of an unusual NRPS. Organic & Biomolecular Chemistry, 8 (14). pp. 3128-3129. ISSN 1477-0520

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Abstract

Feeding phenylalanine analogues to Streptomyces coeruleorubidus reveals the remarkable steric and electronic flexibility of this biosynthetic pathway and leads to the generation of a series of new halopacidamycins.

Item Type: Article
Faculty \ School: Faculty of Science > School of Chemistry
Depositing User: Rachel Smith
Date Deposited: 22 Mar 2011 15:55
Last Modified: 09 Oct 2019 16:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/26912
DOI: 10.1039/C003964K

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