Synthesis of water-dispersible photoluminescent silicon nanoparticles and their use in biological fluorescent imaging

Wang, Qi, Ni, Hongjun, Pietzsch, Annette, Hennies, Franz, Bao, Yongping ORCID: https://orcid.org/0000-0002-6425-0370 and Chao, Yimin ORCID: https://orcid.org/0000-0002-8488-2690 (2011) Synthesis of water-dispersible photoluminescent silicon nanoparticles and their use in biological fluorescent imaging. Journal of Nanoparticle Research, 13 (1). pp. 405-413.

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Abstract

Water-dispersible silicon nanoparticles (Si-NPs) are desirable for applications in biological techniques. A simplified method to synthesize such particles is reported here. The resulting Si-NPs are water-dispersible and luminescent. Under the excitation of UV light, the Si-NPs emit strong red light with a peak maximum at 606 nm and a quantum yield of 6%. They are highly stable, and remain so over several weeks. Fourier Transform Infrared (FTIR) spectroscopy shows a visible Si–CH2 scissoring vibration mode. Furthermore, the surface chemical bondings were confirmed by X-ray photoelectron spectroscopy (XPS). In the Si2p and C1s core levels, Si–C components are observed. The diameters of the synthesized Si-NPS as measured by atomic force microscope (AFM) are approximately 5 nm. Furthermore, the nanoparticles can be taken up by cultured cells. Fluorescence images of Si-NPs within MCF-7 human breast cancer cells show they are distributed throughout the cell tissue.

Item Type:	Article
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Science > School of Chemistry Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Science > Research Groups > Physical and Analytical Chemistry (former - to 2017) Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies Faculty of Science > Research Groups > Chemistry of Materials and Catalysis Faculty of Science > Research Groups > Energy Materials Laboratory
Depositing User:	Rachel Smith
Date Deposited:	21 Mar 2011 12:32
Last Modified:	21 Dec 2022 15:32
URI:	https://ueaeprints.uea.ac.uk/id/eprint/26759
DOI:	10.1007/s11051-010-0047-7

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