Intake of B vitamins in childhood and adult life in relation to psychological distress among women in a British birth cohort

Mishra, Gita D, McNaughton, Sarah A, O'Connell, Maria, Prynne, Celia J and Kuh, Diana (2009) Intake of B vitamins in childhood and adult life in relation to psychological distress among women in a British birth cohort. Public Health Nutrition, 12 (02). p. 166. ISSN 1475-2727

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Abstract

Background - Lower levels of B vitamins (particularly folate, vitamin B12 and vitamin B6) may be associated with psychological distress. Little is known about the impact of childhood nutrition on psychological distress in adult life. Objective - We investigated whether prospectively measured childhood and adult dietary intakes of thiamin, riboflavin, niacin, folate, vitamin B6 and vitamin B12 were related to the psychological distress of women in mid-age, taking into account socio-economic, behavioural and lifestyle factors. Design - Prospective data were collected from a cohort of 636 British women followed up since their birth in 1946. Participants completed a 28-item, scaled version of the General Health Questionnaire (GHQ-28) to measure psychological distress at age 53 years. Dietary intakes in childhood (at age four) were determined by 24h recall and in adulthood (at age 36, 43 and 53 years) by a 5d food record. Results - Low dietary vitamin B12 intake at age 53 was associated with higher psychological distress at that age. Women in the lowest third of vitamin B12 intake in adulthood had a higher GHQ-28 score compared with those in the highest third (percentage change, adjusted regression coefficient, 21 (95% CI 3, 39)). There were no other significant associations between dietary B vitamin intake in childhood or adulthood and psychological distress in the cohort. Conclusions - Overall, there is evidence that intake of vitamin B12 at age 53 is related to adult psychological distress but there is no evidence for the effects of other adult B vitamin intakes or childhood intakes on psychological distress.

Item Type: Article
Faculty \ School: Faculty of Science > School of Pharmacy
Related URLs:
Depositing User: Rachel Smith
Date Deposited: 17 Mar 2011 11:48
Last Modified: 21 Apr 2020 17:42
URI: https://ueaeprints.uea.ac.uk/id/eprint/26504
DOI: 10.1017/S1368980008002413

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