Cognitive performance in children with type 1 diabetes - a meta analysis

Naguib, Justine, Kulinskaya, Elena, Lomax, Claire L. and Garralda, M. Elena (2009) Cognitive performance in children with type 1 diabetes - a meta analysis. Journal of Pediatric Psychology, 34 (3). pp. 271-282. ISSN 0146-8693

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Abstract

Objective: To conduct meta-analyses of neuropsychological performance in young people with type 1 diabetes.  Methods: Meta-analysis of 24 studies. Studies published between 1980 and 2005 were identified. The inclusion criteria were: young people who were ≤19 years of age with type 1 diabetes, a case–control design and standardized neuropsychological tests of seven cognitive domains.  Results: Diabetes was statistically associated with poorer performance on visuospatial ability (d = −0.29), motor speed (d = −0.26) and writing (d = −0.28), on sustained attention (d = −0.21) and reading (d = −0.23). Smaller effects were identified on full IQ (d = −0.14), on performance (d = −0.18) and verbal IQ (d = −0.15). Severe hypoglycemia was linked to deficits in short-term verbal memory (d = −0.14; Confidence Interval: −0.318, 0.024; p =.04).  Conclusions: This meta-analysis indicates that children with type 1 diabetes have mild cognitive impairments and subtly reduced overall intellectual functioning.

Item Type:	Article
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Science > School of Computing Sciences
UEA Research Groups:	Faculty of Science > Research Groups > Data Science and Statistics Faculty of Medicine and Health Sciences > Research Centres > Business and Local Government Data Research Centre (former - to 2023) Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
Depositing User:	Vishal Gautam
Date Deposited:	10 Mar 2011 08:35
Last Modified:	21 Apr 2023 14:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/23751
DOI:	10.1093/jpepsy/jsn074

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