Influence of valve prosthesis type on the recovery of ventricular dysfunction and subendocardial ischaemia folloeing valve replacement for aortic stenosis.

Collinson, Julian, Flather, Marcus, Coats, Andrew J., Pepper, John R. and Henein, Michael (2004) Influence of valve prosthesis type on the recovery of ventricular dysfunction and subendocardial ischaemia folloeing valve replacement for aortic stenosis. International Journal of Cardiology, 97 (3). pp. 535-641. ISSN 1874-1754

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Abstract

Long-standing aortic stenosis (AS) causes significant progressive left ventricular (LV) dysfunction and may result in subendocardial ischaemia. Following aortic valve surgery, LV function may improve and this may be accompanied by reversal of ischaemia. There is debate about the differential effects of valve substitutes. We studied 33 patients with significant AS and impaired LV systolic function. Patients underwent trans-thoracic Doppler echocardiography and 12-lead electrocardiography pre-operatively, prior to discharge from hospital and at 2.5 (range 1.5-3) years follow-up. Twenty patients received a stentless valve and 13 a stented valve. No patient had significant aortic regurgitation, other valvular disease or coronary artery disease. LV fractional shortening (FS) increased from 19±6% to 26±7% post-operatively and to 33±12% at follow-up in the stentless group (p

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: EPrints Services
Date Deposited: 25 Nov 2010 11:13
Last Modified: 24 Jul 2019 16:38
URI: https://ueaeprints.uea.ac.uk/id/eprint/15417
DOI: 10.1016/j.ijcard.2004.03.043

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