Stable isotope pilot study of exchangeable copper kinetics in human blood plasma

Venelinov, Tony I, Beattie, John H, Dainty, Jack R, Hollands, Wendy J, Fairweather-Tait, Susan J and Harvey, Linda J (2007) Stable isotope pilot study of exchangeable copper kinetics in human blood plasma. Journal of Trace Elements in Medicine and Biology, 21 (2). pp. 138-140. ISSN 0946-672X

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Abstract

To develop further our understanding of initial dietary copper metabolism, a method has been developed to separate plasma copper that is bound to albumin, from that bound to ceruloplasmin. This method has been tested using plasma samples from a pilot study involving six human volunteers who consumed 3mg oral doses of the stable isotope (65)Cu and gave blood samples at timed intervals up to 7 days. The results suggest that this method can be used to monitor dynamic fluctuations in newly absorbed copper over a short time frame.

Item Type: Article
Uncontrolled Keywords: albumins,ceruloplasmin,copper radioisotopes,humans,pilot projects,plasma
Faculty \ School:
Faculty of Medicine and Health Sciences > Norwich Medical School
Related URLs:
Depositing User: EPrints Services
Date Deposited: 01 Oct 2010 13:38
Last Modified: 21 Apr 2020 19:34
URI: https://ueaeprints.uea.ac.uk/id/eprint/1528
DOI: 10.1016/j.jtemb.2007.01.001

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