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Venelinov, Tony I, Beattie, John H, Dainty, Jack R 
ORCID: https://orcid.org/0000-0002-0056-1233, Hollands, Wendy J, Fairweather-Tait, Susan J ORCID: https://orcid.org/0000-0002-1413-5569 and Harvey, Linda J
(2007)
Stable isotope pilot study of exchangeable copper kinetics in human blood plasma.
Journal of Trace Elements in Medicine and Biology, 21 (2).
pp. 138-140.
ISSN 0946-672X
Abstract
To develop further our understanding of initial dietary copper metabolism, a method has been developed to separate plasma copper that is bound to albumin, from that bound to ceruloplasmin. This method has been tested using plasma samples from a pilot study involving six human volunteers who consumed 3mg oral doses of the stable isotope (65)Cu and gave blood samples at timed intervals up to 7 days. The results suggest that this method can be used to monitor dynamic fluctuations in newly absorbed copper over a short time frame.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | albumins,ceruloplasmin,copper radioisotopes,humans,pilot projects,plasma |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health |
| Related URLs: | |
| Depositing User: | EPrints Services |
| Date Deposited: | 01 Oct 2010 13:38 |
| Last Modified: | 19 Oct 2023 00:49 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/1528 |
| DOI: | 10.1016/j.jtemb.2007.01.001 |
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