Dietary intake and status of n-3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians, and vegans and the product-precursor ratio [corrected] of a-linolenic acid to long-chain n-3 polyunsaturated fatty acids: results from the EPIC-Norfolk cohort

Welch, AA, Shakya Shrestha, S, Lentjes, M, Wareham, N and Khaw, KT (2010) Dietary intake and status of n-3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians, and vegans and the product-precursor ratio [corrected] of a-linolenic acid to long-chain n-3 polyunsaturated fatty acids: results from the EPIC-Norfolk cohort. American Journal of Clinical Nutrition, 92 (5). pp. 1040-1051. ISSN 1938-3207

Full text not available from this repository. (Request a copy)

Abstract

Background: Intakes of n-3 (omega-3) polyunsaturated fatty acids (PUFAs) are important for health. Because fish is the major source of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), non-fish-eaters may have suboptimal n-3 PUFA status, although the importance of the conversion of plant-derived a-linolenic acid (ALA) to EPA and DHA is debated. Objective: The objective was to determine intakes, food sources, and status of n-3 PUFAs according to dietary habit (fish-eaters and non-fish-eating meat-eaters, vegetarians, or vegans) and estimated conversion between dietary ALA and circulating long-chain n-3 PUFAs. Design: This study included 14,422 men and women aged 39–78 y from the EPIC (European Prospective Investigation into Cancer and Nutrition)-Norfolk cohort with 7-d diary data and a substudy in 4902 individuals with plasma phospholipid fatty acid measures. Intakes and status of n-3 PUFAs were measured, and the precursor-product ratio of ALA to circulating n-3 PUFAs was calculated. Results: Most of the dietary intake of EPA and DHA was supplied by fish; however, meat was the major source in meat-eaters, and spreading fats, soups, and sauces were the major sources in vegetarians. Total n-3 PUFA intakes were 57–80% lower in non-fish-eaters than in fish-eaters, but status differences were considerably smaller. The estimated precursor-product ratio was greater in women than in men and greater in non-fish-eaters than in fish-eaters. Conclusions: Substantial differences in intakes and in sources of n-3 PUFAs existed between the dietary-habit groups, but the differences in status were smaller than expected, possibly because the precursor-product ratio was greater in non-fish-eaters than in fish-eaters, potentially indicating increased estimated conversion of ALA. If intervention studies were to confirm these findings, it could have implications for fish requirements.

Item Type: Article
Additional Information: Erratum in: American Journal of Clinical Nutrition (2011) March 93 (3) 676
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: EPrints Services
Date Deposited: 25 Nov 2010 11:13
Last Modified: 15 Nov 2019 01:12
URI: https://ueaeprints.uea.ac.uk/id/eprint/15250
DOI:

Actions (login required)

View Item View Item