3-D models of cancer biology - Invited Review

Kim, J, Stein, RC and O'Hare, MJ (2005) 3-D models of cancer biology - Invited Review. Seminars in Cancer Biology, 15 (5). pp. 365-377. ISSN 1096-3650

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Three-dimensional (3D) tissue culture models have an invaluable role in tumour biology today providing some very important insights into cancer biology. As well as increasing our understanding of homeostasis, cellular differentiation and tissue organization they provide a well defined environment for cancer research in contrast to the complex host environment of an in vivo model. Due to their enormous potential 3D tumour cultures are currently being exploited by many branches of biomedical science with therapeutically orientated studies becoming the major focus of research. Recent advances in 3D culture and tissue engineering techniques have enabled the development of more complex heterologous 3D tumour models.

Item Type: Article
Uncontrolled Keywords: sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Medicine (former - to 2013)
Depositing User: EPrints Services
Date Deposited: 25 Nov 2010 11:13
Last Modified: 16 Jun 2023 00:14
URI: https://ueaeprints.uea.ac.uk/id/eprint/15133
DOI: 10.1016/j.semcancer.2005.05.002

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