Comparing the performance of the EQ-5D and SF-6D when measuring the benefits of alleviating knee pain

Barton, Garry R., Sach, Tracey H., Avery, Anthony J., Doherty, Michael, Jenkinson, Claire and Muir, Kenneth R. (2009) Comparing the performance of the EQ-5D and SF-6D when measuring the benefits of alleviating knee pain. Cost Effectiveness and Resource Allocation, 7. ISSN 1478-7547

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ABSTRACT: OBJECTIVE: To assess the practicality, validity and responsiveness of using each of two utility measures (the EQ-5D and SF-6D) to measure the benefits of alleviating knee pain. METHODS: Participants in a randomised controlled trial, which was designed to compare four different interventions for people with self-reported knee pain, were asked to complete the EQ-5D, SF-6D, and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at both pre- and post-intervention. For both utility measures, we assessed their practicality (completion rate), construct validity (ability to discriminate between baseline WOMAC severity levels), and responsiveness (ability to discriminate between three groups: those whose total WOMAC score, i) did not improve, ii) improved by >20%, and iii) improved by >/=20%). RESULTS: The EQ-5D was completed by 97.7% of the 389 participants, compared to 93.3% for the SF-6D. Both the EQ-5D and SF-6D were able to discriminate between participants with different levels of WOMAC severity (p > 0.001). The mean EQ-5D change was -0.036 for group i), 0.091 for group ii), and 0.127 for group iii), compared to 0.021, 0.023 and 0.053 on the SF-6D. These change scores were significantly different according to the EQ-5D (p > 0.001), but not the SF-6D. CONCLUSION: The EQ-5D and SF-6D had largely comparable practicality and construct validity. However, in contrast to the EQ-5D, the SF-6D could not discriminate between those who improved post-intervention, and those who did not. This suggests that it is more appropriate to use the EQ-5D in future cost-effectiveness analyses of interventions which are designed to alleviate knee pain. TRIAL REGISTRATION: Current Controlled Trials ISRCTN93206785.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Faculty of Science > School of Pharmacy
Depositing User: EPrints Services
Date Deposited: 25 Nov 2010 11:11
Last Modified: 30 Sep 2021 02:00
DOI: 10.1186/1478-7547-7-12

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