Comparing the performance of the EQ-5D and SF-6D when measuring the benefits of alleviating knee pain

Barton, GR, Sach, TH, Avery, AJ, Doherty, M, Jenkinson, C and Muir, KR (2009) Comparing the performance of the EQ-5D and SF-6D when measuring the benefits of alleviating knee pain. Cost Effectiveness and Resource Allocation, 7. p. 12. ISSN 1478-7547

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ABSTRACT: OBJECTIVE: To assess the practicality, validity and responsiveness of using each of two utility measures (the EQ-5D and SF-6D) to measure the benefits of alleviating knee pain. METHODS: Participants in a randomised controlled trial, which was designed to compare four different interventions for people with self-reported knee pain, were asked to complete the EQ-5D, SF-6D, and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at both pre- and post-intervention. For both utility measures, we assessed their practicality (completion rate), construct validity (ability to discriminate between baseline WOMAC severity levels), and responsiveness (ability to discriminate between three groups: those whose total WOMAC score, i) did not improve, ii) improved by >20%, and iii) improved by >/=20%). RESULTS: The EQ-5D was completed by 97.7% of the 389 participants, compared to 93.3% for the SF-6D. Both the EQ-5D and SF-6D were able to discriminate between participants with different levels of WOMAC severity (p > 0.001). The mean EQ-5D change was -0.036 for group i), 0.091 for group ii), and 0.127 for group iii), compared to 0.021, 0.023 and 0.053 on the SF-6D. These change scores were significantly different according to the EQ-5D (p > 0.001), but not the SF-6D. CONCLUSION: The EQ-5D and SF-6D had largely comparable practicality and construct validity. However, in contrast to the EQ-5D, the SF-6D could not discriminate between those who improved post-intervention, and those who did not. This suggests that it is more appropriate to use the EQ-5D in future cost-effectiveness analyses of interventions which are designed to alleviate knee pain. TRIAL REGISTRATION: Current Controlled Trials ISRCTN93206785.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Faculty of Science > School of Pharmacy
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Depositing User: EPrints Services
Date Deposited: 25 Nov 2010 11:11
Last Modified: 31 Oct 2019 13:39
DOI: 10.1186/1478-7547-7-12

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