Comparing cost-utility estimates: does the choice of EQ-5D or SF-6D matter?

Sach, TH, Barton, GR, Jenkinson, C, Doherty, M, Avery, AJ and Muir, KR (2009) Comparing cost-utility estimates: does the choice of EQ-5D or SF-6D matter? Medical Care, 47 (8). pp. 889-94. ISSN 1537-1948

Full text not available from this repository. (Request a copy)

Abstract

BACKGROUND: A number of different measures can be used within cost-utility analyses, we compared results according to both the EQ-5D and SF-6D. METHODS: A randomized trial was conducted to compare 4 options for people with knee pain. Over the 2 year trial period, the change in cost to health-service was estimated, and both the EQ-5D and SF-6D were used to estimate the change in quality-adjusted life years (QALYs). Using a complete case analysis, the cost-utility (incremental cost-effectiveness ratio [ICER]) of each option, according to both the EQ-5D and SF-6D, was calculated and assessed in relation to the cost-effectiveness threshold of pound20,000 per QALY. RESULTS: Of the 389 participants, 247 had complete cost, EQ-5D and SF-6D data. According to the EQ-5D, option 1 had an estimated ICER of pound10,815 (compared with option 4), option 2 was dominated by option 1, and option 3 was subject to extended dominance. Conversely, according to the SF-6D, option 3 had an ICER of pound9999 (compared with option 4), option 2 had an ICER of pound36,883 (compared with option 3), and option 1 was subject to extended dominance. CONCLUSION: The EQ-5D and SF-6D estimated that different options (1 and 3, respectively) were cost-effective at the pound20,000 per QALY threshold, demonstrating that the choice of measure does matter.

Item Type: Article
Additional Information: Source:HEG-endnote12-09 Note:
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Faculty of Science > School of Pharmacy
Related URLs:
Depositing User: EPrints Services
Date Deposited: 25 Nov 2010 11:11
Last Modified: 31 Oct 2019 13:42
URI: https://ueaeprints.uea.ac.uk/id/eprint/14142
DOI: 10.1097/MLR.0b013e3181a39428

Actions (login required)

View Item View Item