The effect of moderate alcohol consumption on bone mineral density: a study of female twins

Williams, F. M. K., Cherkas, L. F., Spector, T. D. and MacGregor, A. J. ORCID: https://orcid.org/0000-0003-2163-2325 (2005) The effect of moderate alcohol consumption on bone mineral density: a study of female twins. Annals of the Rheumatic Diseases, 64 (2). pp. 309-310. ISSN 1468-2060

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Abstract

Background: Osteoporosis is associated with morbidity and mortality, particularly in postmenopausal women. The effect of moderate alcohol intake on bone mineral density (BMD) and fracture risk remains unclear. Objective: To carry out a twin study to investigate this effect while controlling for genetic effects and other confounding variables. Methods: BMD was determined at the hip and lumbar spine in 46 pairs of monozygotic twins discordant for alcohol consumption. Biochemical evidence of altered bone metabolism was sought. Results: A positive association between alcohol consumption and BMD was shown, in contrast to the negative effect of smoking on BMD. Markers of bone turnover were not associated with alcohol or BMD. Conclusions: Moderate alcohol consumption is not harmful to bone health in women and may even be beneficial. Beneficial effects do not appear to be mediated through an action on bone metabolism.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Science > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine
Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health
Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023)
Depositing User: EPrints Services
Date Deposited: 25 Nov 2010 11:11
Last Modified: 16 Jul 2024 09:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/13977
DOI: 10.1136/ard.2004.022269

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