Poor reporting and inadequate searches were apparent in systematic reviews of adverse effects

Golder, Su, Loke, Yoon and McIntosh, Heather M. (2008) Poor reporting and inadequate searches were apparent in systematic reviews of adverse effects. Journal of Clinical Epidemiology, 61 (5). pp. 440-448. ISSN 1878-5921

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Abstract

Objective: Systematic reviews incorporating adverse effects are assuming increasing importance as questions raised extend beyond clinical effectiveness to all effects (beneficial and harmful). The aim of this study was to survey the methods used to identify relevant studies for systematic reviews of adverse effects. Study Design and Setting: All records within the Database of Abstracts of Reviews of Effects and the Cochrane Database of Systematic Reviews were scanned for systematic reviews in which the primary outcomes were adverse effects. Two information professionals independently assessed the methods used to identify relevant research as reported in the 277 reviews that met the inclusion criteria. Results: A major weakness of the reviews was inadequate reporting of the search strategies used. In addition, of the reviews that did report a search strategy, few used the sensitive search strategies recommended for systematic reviews. The majority of reviews did not search more than one or two databases, and few other methods of identifying information were used. Conclusion: This investigation shows the variation in the searching element of systematic reviews of adverse effects and demonstrates that the reporting of the methods used to identify research in such reviews could be vastly improved.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Health Services and Primary Care Faculty of Medicine and Health Sciences > Research Centres > Population Health Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Depositing User:	EPrints Services
Date Deposited:	25 Nov 2010 11:09
Last Modified:	28 Mar 2025 03:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/12664
DOI:	10.1016/j.jclinepi.2007.06.005

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