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ToolsCanoy, Dexter, Luben, Robert, Welch, Ailsa, Bingham, Sheila, Wareham, Nicholas, Day, Nicholas and Khaw, Kay-Tee (2004) Fat distribution, body mass index and blood pressure in 22,090 men and women in the Norfolk cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) study. Hypertension, 22 (11). pp. 2067-2074.
Full text not available from this repository. (Request a copy)Abstract
Objective: To determine the relation between fat distribution and blood pressure, independent of body mass index. Design: Cross-sectional, population-based study. Participants and methods: Participants, 9936 men and 12 154 women aged 45–79 years, were recruited from general practices in Norfolk, United Kingdom for the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) study. Participants filled in a health and lifestyle questionnaire and their blood pressure and anthropometry were measured at a clinic. We mainly used waist–hip ratio (WHR) to assess body fat distribution. Results: Systolic blood pressure (SBP) and diastolic blood pressure (DBP) increased linearly across the whole range of waist–hip ratio in both men and women. The relation was independent of age, body mass index (BMI) and other covariates. Separately, waist and hip circumferences were positively related to SBP and DBP. When adjusted for BMI, waist circumference was positively related to SBP (in women) and DBP (in both men and women), whereas hip circumference was inversely related to SBP (but not DBP) in both men and women. Stratifying by tertiles of waist and hip circumference, age- and BMI-adjusted SBP and DBP were highest among those with high waist and small hip circumference measures. Conclusion: Waist–hip ratio was independently related to blood pressure. Waist–hip ratio could reflect the separate and opposite relations of waist and hip circumferences on blood pressure. Characterizing patterns of fat distribution may have implications in the assessment and control of obesity-related blood pressure elevation.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Medicine and Health Sciences > Research Centres > Population Health |
| Depositing User: | EPrints Services |
| Date Deposited: | 25 Nov 2010 11:09 |
| Last Modified: | 15 Jul 2025 11:30 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/12279 |
| DOI: | 10.1097/00004872-200411000-00007 |
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