The role of spalt proteins in development and disease

Sweetman, Dylan and Munsterberg, Andrea ORCID: (2006) The role of spalt proteins in development and disease. Developmental Biology, 293 (2). pp. 285-293. ISSN 1095-564X

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The spalt proteins are encoded by a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans and vertebrates. In humans, mutations in some of these genes are associated with several congenital disorders which underscores the importance of spalt gene function in embryonic development. Recent studies have begun to cast light on the functions of this family of proteins with increasing understanding of the developmental processes regulated and the molecular mechanisms used. Here we review what is currently known about the role of spalt genes in vertebrate development and human disease.

Item Type: Article
Faculty \ School: Faculty of Science > School of Biological Sciences
UEA Research Groups: Faculty of Science > Research Groups > Cells and Tissues
Depositing User: EPrints Services
Date Deposited: 01 Oct 2010 13:38
Last Modified: 22 Apr 2023 01:33
DOI: 10.1016/j.ydbio.2006.02.009


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