Antigenic variation in pathogenic micro-organisms: similarities and differences

Steverding, D (2007) Antigenic variation in pathogenic micro-organisms: similarities and differences. African Journal Microbiol Research, 1 (7). pp. 104-112.

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Antigenic variation is a process by which pathogenic micro-organisms escape the immune response of their mammalian hosts. By convergent evolution, protozoal, fungal and bacterial pathogens have developed similar genetic mechanisms for true antigenic variation. In this review article, the biology, the surface antigens and their encoding genes, and the molecular mechanisms of antigenic variation of the protozoa Trypanosoma brucei, Plasmodium falciparum, Babesia bovis, Giardia lamblia, the fungus Pneumocystis carinii, and the bacteria Borrelia hermsii, Anaplasma marginale, Neisseria gonorrhoeae, Mycoplasma bovis and Campylobacter fetus are compared.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: EPrints Services
Date Deposited: 25 Nov 2010 11:08
Last Modified: 08 Sep 2021 00:24

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